We then developed a suite of opioid domain–specific text mining techniques (eg, opioid jargon detection and opioid trading information retrieval) to recognize information relevant to opioid trading activities (eg, commodities, price, shipping information, and suppliers). Subsequently, we conducted a comprehensive, large-scale, longitudinal study to demystify opioid trading activities in anonymous markets and forums. Our study identified 41,000 opioid trade–related marketplace listings and forum posts by analyzing more than 1 million listings and posts in multiple anonymous marketplaces and forums, which is the largest underground opioid trading data set ever reported.
Huge Brazilian raid on Rio gang leaves at least 60 people dead and 81 under arrest
The results show that vendors’ trustworthiness is a better predictor of vendor selection than product diversity or affordability. Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis. Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing. Cherian et al [12] gathered codeine misuse data from Instagram posts to understand how misuse is happening and its misused form. However, to the best of our knowledge, no large-scale study, which may cross multiple anonymous marketplaces and is cross-sectional, has been conducted to profile the opioid supply chain and unveil characteristics of opioid suppliers, commodities, and transactions. To the best of our knowledge, a comprehensive overview of the opioid supply chain in the anonymous online marketplaces and forums, as well as a measurement study of trading activities, is still an open research challenge.
Toronto Public Health (Toronto)
- Thus, we identified 58 opioid jargon used in the anonymous marketplaces and forums (Table 2).
- Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs.
- These background papers were commissioned by the EMCDDA and Europol to provide background information to inform and contribute to the drafting of the main report.
- The results provide insight into opioid trading in the anonymous markets and forums and may prove an effective mitigation data point for illuminating the opioid supply chain.
- To identify forum posts related to opioid commodity promotion and review, our methodology was designed to filter forum posts with opioid keywords and then use a classifier to the posts with the topics of interest.
- To this end, we first collected the marketplace’s lifespan using the Gwern archive [37], as shown in Table 1, and then compared the supplier lists in each marketplace to investigate supplier migration.
- We manually investigated the results by randomly sampling 10% of data records during each iteration and adding false positive samples into the unlabeled set.
- On the way home, they made some side stops to pick up drugs and got high and drunk together.
Like any marketplace, branding is key, even in the shadowy corners of the internet. But this logo, created using Adobe Illustrator version 24.0—a software outdated as of 2019—became the first crack in DrugHub’s armor. Embedded within the logo’s metadata was a treasure trove of information for anyone skilled in Open Source Intelligence (OSINT). The use of outdated software was not just a cosmetic flaw; it signaled a broader negligence in keeping up with technological advancements.
Platform
ω
Links to NCBI Databases
On the way home, they made some side stops to pick up drugs and got high and drunk together. These shadow operators have been romanticized in Hollywood films that present them in the archetype of the rugged frontiersman and cowboy who does what is necessary to defeat the nation’s evil, and invariably, dark-skinned foes. The first challenge is solving a captcha (sliding a circle into position, similar to Incognito Market’s captcha).
- We manually validated all keywords and the corresponding categories to guarantee their correctness.
- Combining opioid jargon with known opioid product names [25-27], we generated an opioid keyword data set consisting of 311 opioid keywords with 13 categories.
- The papers have been cited within the report and are also being made available here for those who would like further information on the topic.
- However, to the best of our knowledge, no large-scale study, which may cross multiple anonymous marketplaces and is cross-sectional, has been conducted to profile the opioid supply chain and unveil characteristics of opioid suppliers, commodities, and transactions.
- Funds are automatically transferred to our secure escrow system, protectingboth buyer and vendor interests.
Access
This is because the same user could have different IDs, and the same ID in different marketplaces can point to different users. Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs. The global market for pancreatic and bile duct cancer therapeutics is experiencing significant growth driven by advancements in targeted therapies, increasing prevalence of these cancers, and expanding research initiatives. The rising adoption of personalized medicine and innovative drug delivery systems further contribute to market expansion.
US to share biometric data with Chile ‘to track criminals,’ Homeland Security’s Noem says
We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities. Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. Our research collected product listings and forum posts from 10 anonymous online market places and 6 forums. Our study determined the underground marketplace and forum list based on darknet site search engines and previous research works [20]. More specifically, we used darknet site search engines (such as Recon, Darknet live, Dark Eye, dark.fail, and DNStats [21,22]) to search underground marketplaces and forums and then manually validated their activeness. Note that some high-profile underground marketplaces and forums are frequently deactivated or have been shut down by law enforcement authorities [23].
Internal Links
- In the above objective function, C+ is always larger than C−, which means that the penalty of misclassifying a positive instance is larger than that of a negative instance.
- Secure escrow system holds funds for 7-21 days depending on productcategory, with automatic release upon delivery confirmation or disputeresolution through our moderation team.
- 🔐 Built on robust security protocols, leveraging Monero (XMR) for completeprivacy and anonymous transactions.
- Quintana et al [16] and Fernando et al [17] presented the results of the international drug testing service for opioid commodities from the anonymous marketplaces and showed that most opioid substances contained the advertised ingredient and most samples were of high purity.
- Market Research Intellect (MRI) is a trusted provider of comprehensive market intelligence, delivering actionable insights that enable businesses to make informed, strategic decisions.
- Like any marketplace, branding is key, even in the shadowy corners of the internet.
Our experiment evaluated MALLET on our annotated anonymous marketplace and forum data set (Table 3) using 3 classification algorithms in the document classification tool (package cc.mallet.classify class in MALLET’s JavaDoc API [Application Programming Interface]). We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic. The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation. We used the metrics of precision and recall to compare the performance of different topic modeling methods. As shown in Table 4, our results indicate that our approach significantly outperforms MALLET and the baseline model in terms of both precision and average recall.
Key Features
All communications and sensitive data are protected using Pretty GoodPrivacy (PGP) encryption with 4096-bit keys, ensuring complete privacy fromthird-party interception. This onion is protected by custom sophisticated CAPTCHA systems and POWenabled to give you the best experience using DrugHub market. This said… at this point in time I would not be surprised if DrugHub has been had it’s servers imaged by Law Enforcement and investigations at this point are probably underway. The Ministry of Health works to help people stay healthy, delivering high-quality care when they need it and protecting the health system for future generations.
Demystifying the Dark Web Opioid Trade: Content Analysis on Anonymous Market Listings and Forum Posts
- When you donate to CovertAction Magazine, you are supporting investigative journalism.
- In addition, J&J kicked off 2026 by announcing plans to build a next-generation cell therapy manufacturing site in Pennsylvania.
- To collect the listing information of 5 anonymous online marketplaces (ie, Apollon, Avaris, Darkbay, Empire, and The Versus Project), we conducted a whole-site crawl.
- First, we designed and implemented an anonymous marketplace data collection and analysis pipeline to gather and identify opioids data in 16 anonymous marketplaces and forums over a period of almost 9 years between 2011 and 2020.
- Government initiatives aimed at improving cancer screening and treatment infrastructure are pivotal.
We manually investigated the results by randomly sampling 10% of data records during each iteration and adding false positive samples into the unlabeled set. The review detection model yielded a mean precision of 81.5% and an average recall drug hub of 80.1%, whereas for the promotion detection model, it yielded a mean precision of 88.1% and an average recall of 85.1% (Table 4). At Market Research Intellect, our mission is to bridge the gap between data and decision-making.
- Europol said that 288 suspects were arrested and more than 50.8 million euros ($53.4 million) in cash and virtual currencies, 850 kilograms of drugs and 117 firearms were seized in a series of raids in several countries.
- It is comprehensive but accessible and policy-oriented, intended to facilitate discussions at EU-level on how to respond to darknet drug markets, whilst identifying key priority areas that require attention and where activities are likely to have most impact.
- In addition, we set parameters such as sleeping time to limit the speed of crawling.
- DrugHub Market is the top darknet marketplace from the team behind White House Market.
- In general, the correlation between the penalty factors and the number of samples is set as , where P and C are the sizes of Dp and Dc, respectively.
- Experience the future of secure, anonymous trading with Drughub Market’scutting-edge platform and trusted community.
- As observed in our data set, the top 3 marketplaces with the most opioid listings are Agora, Evolution, and Apollon.
- Our opioid jargon identification procedure implemented a modified semantic comparison model [19].
PGP Public Keys
We partner with organizations of all sizes—from startups to Fortune 500 companies—to help them optimize strategies, strengthen competitiveness, and drive sustainable growth. Our commitment to quality research and client success has established us as a trusted name in global market intelligence. The Pancreatic And Bile Duct Cancer Drug Market refers to the global industry involved in the development, production, and deployment of Pancreatic And Bile Duct Cancer Drug solutions across various end-use sectors. He hung around with a rough crowd of Special Forces operatives in Fayetteville who drank heavily, took copious amounts of drugs and told graphic war stories in each others’ company while boasting about the numbers of people they had killed. The layout, coded from scratch, is different from White House Market but remains intuitive for experienced darknet users. Experience the future of secure, anonymous trading with Drughub Market’scutting-edge platform and trusted community.
DrugHub Market
Become part of the #1 darknet marketplace trusted by over 500,000 users and 100k+ listings. Frost & Sullivan Best Practices Awards recognize companies in various regional and global markets for demonstrating outstanding achievement and superior performance in leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analyses, and extensive secondary research to identify best practices in the industry.
Can we really reverse gray hair? Insights from latest study
This link is updated to provide DDoSprotection and has POW protection enabled, it might take a couple of minutesto establish a connection. As you can see DrugHub.link & DrugHub.su use the same IP address although it might seems suspicious that drughub.su would be seen using Cloudflare as of Today & DrugHub.link would be seen using an IP that was never updated between today and the November 25th 2024. Europol said that 288 suspects were arrested and more than 50.8 million euros ($53.4 million) in cash and virtual currencies, 850 kilograms of drugs and 117 firearms were seized in a series of raids in several countries. The facilities, which the province is calling HART hubs, are part of the Progressive Conservative government’s marked shift away from harm reduction policies and toward a focus on addictions treatment and recovery.
The government’s focus on expanding cancer treatment centers and facilitating access to modern therapeutics are fostering market development. The presence of international pharmaceutical companies and ongoing research collaborations further enhance treatment options. As the healthcare system continues to evolve, Sri Lanka is positioning itself as a key player in regional cancer management, with an emphasis on innovative therapies and patient-centric care models. Anonymous online marketplaces are usually platforms for sellers and buyers to conduct transactions in a virtual environment.
This can be either an onion site or a clearnet mirror that’s only accessible using the Tor browser. Enhanced account security through mandatory 2FA implementation usingtime-based one-time passwords (TOTP), preventing unauthorized access even ifcredentials are compromised. In case of marketplace downtime or critical issues preventing normal support access, check this clearnet website for announcements.
Hamilton Urban Core Community Health Centre (Hamilton)
Emerging markets are showing promising potential due to improving healthcare infrastructure and heightened awareness. This analysis provides a comprehensive overview of the current market landscape, key regional trends, and the technological innovations shaping the future of pancreatic and bile duct cancer treatments across diverse geographic regions. This joint report prepared by the EMCDDA and Europol considers the latest findings from international research, fresh empirical data, and operational information and intelligence in order to illuminate how darknet markets function and how they relate to criminal behaviour. It is comprehensive but accessible and policy-oriented, intended to facilitate discussions at EU-level on how to respond to darknet drug markets, whilst identifying key priority areas that require attention and where activities are likely to have most impact. As observed in our data set, the opioid suppliers in the marketplaces Evolution, Pandora, and Silk Road accepted escrow as a method of payment. In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39].
New vendors without an existing darknet marketplace history can join Drughub Market by paying a $1000 securitydeposit. This deposit reinforces trust on the Drughub darknet, ensures a commitment to high-qualityservice, and acts as insurance against potential disputes. Access Drughub market onion links or official Drughub mirrors to get started today. Always verify the complete onion URL character by character before entering any credentials.
This finding is roughly in line with the observation of 57 opioid vendors’ origin in a marketplace named Cryptomarket during the period of October 2015 through April 2016, which was reported by Duxbury et al [6]. In addition, we did not observe big changes in the top opioid commodity origins from 2014 to 2020. Particularly, as shown in Table 8, the United States and the United Kingdom are always in the top 5 advertised origins among years. Co-occurrence of the same opioid suppliers across different anonymous marketplaces. We compared our method with the state-of-the-art topic modeling method Machine Learning for Language Toolkit (MALLET) [30] and our model without transfer learning stage (baseline).
Revolutionizes pre-clinical and clinical drug development through its cutting-edge organoid technology, enhancing its accuracy and efficiency. Market Research Intellect (MRI) is a trusted provider of comprehensive market intelligence, delivering actionable insights that enable businesses to make informed, strategic decisions. With a focus on accuracy, depth, and relevance, we specialize in analyzing global markets across diverse industries including healthcare, technology, chemicals, consumer goods, energy, and more.